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Chang Yee Hong  (Hong CY) 124 Articles
Original Article
Atrial Rhythms in Patients with Left Atrial Isomerism
Jae Kon Ko, Young Mee Suh, Young Hwee Kim, In Sook Park, Chang Yee Hong
Clin Exp Pediatr. 1999;42(11):1535-1541.   Published online November 15, 1999
Purpose : Histologic studies have revealed ectopic location and hypoplasia of sinus nodal tissue in left atrial isomerism. The purpose of this study is to characterize the atrial rhythms corresponding to these histologic abnormalities in left atrial isomerism. Electrocardiograms in left atrial isomerism are characterized by multiple atrial rhythms with abnormal P-wave axes, but the complex nature of atrial rhythms...
Early Results of Radiofrequency Catheter Ablation of Supraventricular Tachycardia in Children
Jae Kon Ko, Young Hwee Kim, Young Hwee Kim, Chang Yee Hong, Jae Joong Kim, You Ho Kim
Clin Exp Pediatr. 1997;40(9):1258-1264.   Published online September 15, 1997
Purpose : Although the data of radiofrequency catheter ablation(RFCA) of supraventricular tachycardia in adults has been accumulated in several centers in Korea, few data are available on its efficacy and safety in pediatric ages. We reviewed the data in young patients who underwent this procedure in a pediatric cardiology center, to evaluate the indications, early results, complications, and short-term follow-up data. Methods : We retrospectively...
Case Report
Four Cases of Pulmonary Artery Sling with Bridging Bronchus
Seung A Lee, Jung Yeon Shim, Young Hwue Kim, Jae Kon Ko, In Sook Park, Soo-Jong Hong, Chang Yee Hong
Clin Exp Pediatr. 1997;40(5):709-715.   Published online May 15, 1997
Pulmonary artery sling with bridging bronchus is not only rare but also difficult to diagnose unless specially sought. When young infant suffers from prolonged or recurrent wheezing, possibility of underlying anomalies of the tracheobronchial trees or great vessels should be considered, even though bronchiolitis and gastroesophageal reflux are the most common causes. We experienced four cases of pulmonary artery sling with...
Original Article
Tachycardia Induced Cardiomyopathy in Children
Jae Kon Ko, Young Hwee Kim, In Sook Park, Chang Yee Hong
Clin Exp Pediatr. 1997;40(1):55-62.   Published online January 15, 1997
Effect of Recombinant Human Erythropoietin on the Anemia of Premature Infants
Young Ah Lee, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1996;39(5):631-640.   Published online May 15, 1996
Purpose : To determine whether the prophylactic treatment with recombinant human erythropoietin(rHuEPO) for the anemia of prematurity would reduce the need for blood transfusions. Methods : We randomly assigned 17 premature infants to therHuEPO group and the control group. For the rHuEPO group (n=9, birth weight=1210¡¾156 g, gestational age=31.7¡¾1.9wk), rHuEPO (400U/kg) was given three times a week for 4 weeks, plus iron (8 mg/kg/day) and vitamin...
The Study of Distribution of HI Antibody Titers Aganist Japanese Encephalitis Virus Among Children in Seoul
Jin A Kim, Tae Sung Ko, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Hae Wol Cho
Clin Exp Pediatr. 1996;39(2):230-237.   Published online February 15, 1996
Purpose : Incidence of Japanese encephalitis has been markedly decreased, but this disease is known to be high and lethal in the young age group. This study was designed to find out the HI antibody titers and associated factors of Japanese encephalitis of children in Seoul, and to establish the plan of vaccination. Methods : The survey was conducted from the...
Case Report
Catheter Ablation of Atrial Flutter Using Radiofrequency Energy in a Child :A Case Report
Jae Kon Ko, In Sook Park, Young Hwee Kim, Chang Yee Hong, Jae Joong Kim, You Ho Kim
Clin Exp Pediatr. 1996;39(10):1455-1460.   Published online October 15, 1996
Atrial flutter is a potentially life threatening complication of repair or palliation of congenital heart disease and is frequently drug resistant. Recent studies in human have demonstrated that common type atrial flutter is due to macro-reentry in the right atrium and that the reentrant circuit may involve slow conduction in the low posteroseptal area of the right atrium. Catheter ablation of atrial flutter has...
A Case Report : Ganciclovir Therapy of Cytomegalovirus Pneumonitis
Jee-Yeon Min, Soo-Jong Hong, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1996;39(1):142-147.   Published online January 15, 1996
Ganciclovir is an antiviral agent that is effective for cytomegalovirus (CMV) infection in immunocompromised hosts. But the benefits of treatment for the congenital CMV diseases are still controversial. Cytomegalovirus pneumonitis is very rare. And so, a few cases of ganciclovir therapy in CMV pneumonitis were reported. We experienced a case of a 7 month-old male infant with prolonged pneumonitis and respiratory difficulty...
Original Article
Clinical and Histologic Changes in Children with Chronic Hepatitis B Virus Infection after Alpha Interferon Therapy
Kyung Mo Kim, Soo Jong Hong, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Joo Ryoung Huh
Clin Exp Pediatr. 1995;38(9):1232-1241.   Published online September 15, 1995
Purpose : Several trials in children for chronic hepatitis B have shown the efficacy of alpha interferon in eliminating hepatitis B virus replication, accompanied by an improvement in the liver cell damage. But reports about the alpha interferon therapy are rare in Korean children and there is no report about histologic changes even with adult. So we tried to...
Prevalence of Epstein-Barr Virus (EBV) Antibody in Korean Children
Sei Ho Oh, Young Ah Lee, Woong Young Moon, Tae Sun Won, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Won Kim
Clin Exp Pediatr. 1994;37(6):804-811.   Published online June 15, 1994
Recently, cases with typical clinical manifestations of infectious mononucleosis are increasing in Korea. So, to evaluate the recent epidemiology of EBV infection in Korea, we performed EBV serologic antibody tests for IgG antibody to EBV-viral capsid antigen (VCA) and antibody to EBV-associated nuclear antigen (EBNA) among the 108 healthy Korean infants and children whose ages were from newborn to 15...
Infectious Mononucleosis in Children
Woong Young Moon, Sei Ho Oh, Tae Sung Ko, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Won Kim
Clin Exp Pediatr. 1994;37(6):822-831.   Published online June 15, 1994
We reviewed th eclinical findings of infectious mononucleosis and performed Epstein-Barr virus (EBV) serologic antibody tests in infectious mononuleosis and healthy group. One group was 18 cases of children, diagnosed as infectious mononucleosis who had been admitted to the department of Pediatrics. Asan Medical Center for two years and eight months. From November, 1989 to June, 1992. Another group was...
Case Report
A Case of Rett Syndrome Observed with Video-EEG Monitoring
Hyun Mi Kim, Young Ah Lee, TaecSung Ko, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1994;37(5):718-725.   Published online May 15, 1994
Rett syndrome is progressive neurodegenerative disorder in female patients, characterized by autistic behavior, mental retardation, loss of purposeful hand skills, sterotypic hand movement, breathing dysfunction, severely impaired language, ataxia, and seizure. The diagnosis of Rett syndrome is based on its characteristic clinical manifestation and course. The electroencephalographic(EEG) findings of Rett syndrome are nonspecific, but a progressive deteriorationin the EEF, characterized...
Original Article
Hand, Foot and Mouth Disease Associated with the Aseptic Meningitis in Seoul, 1990
Young Ah Lee, Sei Ho Oh, Soo Jong Hong, Young Hwue Kim, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1993;36(6):842-849.   Published online June 15, 1993
We performed clinical and virological studies on 79 children with hand, foot and mouth disease(HFMD) who had been admitted or visited to the department of Pediatrics, Asan Medical Center from February to August, 1990. The results were as follows; 1) There were total of 79 cases with hand, foot and mouth disease during this period. The aseptic meningitis was combined in 18cases(22.8%) 2)...
A Clinical Study on Aseptic Meningitis Combined with Polio-Like Paralysis
Woong Young Moon, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Chul Suh, Si Joon Yu, In Young Seong, Young Min Ahn
Clin Exp Pediatr. 1993;36(4):485-494.   Published online April 15, 1993
We clinically reviewed four patients who were suffering from aseptic meningitis combined with polio-like paralysis and performed radiological, neurological and virological studies on them. Three patients were admitted to the department of Pediatrics. Asan Medical Center from March to August 1990, and one patient was admitted to the department of Pediatrics, Kangnam General Hospital. The results were as follows: 1) During the period...
Aseptic Meningitis in 1991 - isolation of causative agent -
Yoon Ah Park, Eun Young Cho, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1993;36(4):506-511.   Published online April 15, 1993
To know the causative agent of asptic meningitis, we performed blood and cerebrospinal fluid study on 24 children who had been admitted to the department of Pediatrics, Asan Medical Reference Laboratory, Japan. The most of the patients were young infants, and 15 cases of them were under 3 months of age. The male to female ratio was 1:1.4. We observed the main symptoms...
Influenza Epidemic in the Pediatric Patients in Seoul 1991
Hyun Mi Kim, Se Ho Oh, Eun Young Cho, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Young Suhn Kim, Kee Duk Park
Clin Exp Pediatr. 1993;36(3):379-385.   Published online March 15, 1993
Influenza virus culture was performed in 149 patients with influenza-like illness who were admitted or visited to the Department of Pediatrics, Asan Medical Center from january 1991 to March,1991. The results were as follows : 1) Of the total 149 patients, influenza virus were isolated in the 15 cases. : 15 isolates were characterized by the WHO Collaborating Center for influenza : 7...
Hepatic Rickets in Infancy with Neonatal Hepatitis
Mi Koo Kang, Eun Young Cho, Soo Jong Hong, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1992;35(4):527-533.   Published online April 15, 1992
We had treated a hepatic rickets in 6 infants with neonatal hepatitis from June 1989 to August 1990 at Asan Medical Center. The results were as follows 1) Age of 6 patients were below 4 months and 4 patients were male, 2 patients were female. 2) The clinical findings were hepatosplenomegaly(5 cases), jaundice(4 cases), craniotabes (4 cases), failure to thrive(2 cases), hypocalcemiac seizure(2...
Treatment of Kawasaki Disease with Single High-dose Intravenous Gammaglobulin
Mi Koo Kang, Eun Young Cho, Young Hwue Kim, Ki Soo Kim, Young Seo Park, In Sook Park, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1992;35(3):342-348.   Published online March 15, 1992
Kawasaki disease is an acute febrile illness of unknown origin and most frequently affects infants and children under 5 years of age. Coronary aneurysms are the most serious complications and 15-20% of patient develop coronary aneurysm. We studied 50 children who wre diagnosed as Kawasaki disease and treated simultaneously with single high-dose gammaglobulin (2 gm/kg/day) and aspirin at Asan Medical Canter...
Balloon atrial septostomy through umbilical vein approach using flexible guide wire and sheath technique.
In Sook Park, Ki Soo Kim, Chang Yee Hong, Shi Joon Yoo
Clin Exp Pediatr. 1991;34(9):1294-1298.   Published online September 30, 1991
Balloon atrial septostomy is accepted as the best initial palliative treatment in infants with certain types of cyanotic congenital heart disease and the importance of prompt creation of atrial communi- cation can not be overemphasized in these patients. Balloon atrial septostomy is performed through femoral vein using percutaneous technique in most cases and is rarely done by cut down approach. However, percutaneous femoral vein...
Tricuspid atresia associated with double orifice mitral valve and coronary sinus septal defect.
In Sook Park, Ki Soo Kim, Young Seo Park, Chang Yee Hong, Shi Joon Yoo, Meong Gun Song
Clin Exp Pediatr. 1991;34(8):1139-1145.   Published online August 31, 1991
Clinical, echocardiographic and angiographic findings of a very rare case of cardiac malformation is presented. The main features were tricuspid atresia, coronary sinus septal defect, and double orifice mitral valve. These defects were correctly diagnosed by echocardiography and were confirmed by angiocardiography. This patient was palliated successfully with blade balloon atrial septostomy and bidirectional cavopulmonary shunt. To the best of our knowledge, this is the...
Blade atrial septostomy in infants with cyanotic congenital heart diseases.
In Sook Park, Young Hwue Kim, Chang Yee Hong
Clin Exp Pediatr. 1991;34(12):1655-1663.   Published online December 31, 1991
In patients with certain types of congenital heart malformations, an adequate interatrial communi- cation is essential for survival and balloon atrial septostomy (BAS) is a life saving procedure in these infants. However, BAS alone is not successful in older infants and children with thickened atrial septum, and blade septostomy is indicated in these situations. This procedure so far has not been reported in Korean literature...
Epidemics of aseptic meningitis in Seoul area during 1989-90.
Eun young Cho, Mi Koo Kang, Soo Jong Hong, Ki Soo Kim, Young Seo Park, In Sook Park, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1991;34(11):1565-1572.   Published online November 30, 1991
We performed clinical and virological studies on 200 children with aseptic meningitis who had been admitted to the department of Pediatrics, Asan Medical Center from June, 1989 to August, 1990. The results were as follows; 1) There were total of 236 meningitis cases during this period, 13(5.5%) with bacterial meningitis, 3(1%) with tuberculous meningitis, 220(93.2%) with aseptic meningitis. Am이lg aseptic meningitis, 20(8.5%) were mumps meningitis. 2) Aseptic meningitis...
Studies on Arrhythmias in School Children.
Young Hwue Kim, Hann Tchah, Ki Soo Kim, Chung Il Noh, Jung Yun Choi, Young Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1989;32(8):1093-1097.   Published online August 31, 1989
To determine the incidence of cardiac arrhythmias of the school children, we have performed heart screening by the questionare and EKG and physical examination from September 1984 to October 1987 in Seoul. 1) The incidence of the cardiac arrhythmias was 1.27%. 2) There were 449 cases of heart diseases detected. Among these heart diseases there were congeni- tal heart diseases in 82 cases (0.31%), acquired heart diseases...
A Study on Blood Pressure Measurements in School Children in Seoul Area.
Young Choi, Chang Youn Lee, Chung Il Noh, Chang Yee Hong, Sang Il Lee
Clin Exp Pediatr. 1989;32(8):1086-1092.   Published online August 31, 1989
Blood pressure measurements were done in 9,346 school children in Seoul area in May, June and September, 1987. Korin BP 103N (automated oscillometric method) was used for blood pressure measurements. The results were as follows. 1) Blood pressure increased according to both increasing age and height. 2) Mean systolic pressure (MSP) increased from 100 mmHg at 6 to 124 mmHg at 18 years of age in boys. On...
Clinical Characteristics of Ventricular Tachycardia on 24 hour ECG in Children.
Ki Soo Kim, Young Hwue Kim, Chung Il Noh, Jung Yun Choi, Yong Soo Yoon, Chang Yee Hong
Clin Exp Pediatr. 1989;32(7):958-964.   Published online July 31, 1989
Ventricular tachycardia (VT) is uncommon, but is in increasing tendency probably due to better case detection and longer survival of the patients with complex congenital heart disease. Widespread use of 24 hour ECG has contributed a lot to better understanding of ventricular tachycardia. Fourteen cases of ventricular tachycardia diagnosed by 24 hour ECG at Seoul National Children’ s Hospital from Feb. 1986 to Sep....
Clinical Observation on Amiodarone Treatment for Critical Arrhythmia in Children.
Ki Soo Kim, Chung Il Noh, Jung Yun Choi, Yong Soo Yoon, Chang Yee Hong
Clin Exp Pediatr. 1989;32(6):765-772.   Published online June 30, 1989
Sixteen cases of critical arrhythmia in children were prospectively studied at the department of pediatrics, Seoul National University Hospital, from Oct. 1986 to Apr. 1988 in order to determine the efficacy and side effect of amiodarone treatment in children. Their ages ranged from 5 months to 17 years with 2 patients younger than 1 year of age. The most frequent indication of amiodarone treatment...
Clinical Study on Asplenia and Polysplenia Syndrome.
Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1989;32(5):653-658.   Published online May 31, 1989
The clinical characteristics of sixteen cases of asplenia and four cases of polysplenia were studied at Seoul National University Hospital from October 1986 to February 1988. Cardiac anomalies were confirmed by echocardiography and cardiac catherization. Splenic status was confirmed by abdominal aortography in most cases. Mean age of asplenia was 1 year 10 months and that of polysplenia was 8 years 6 months. Male-Female...
The Collaborative Clinical Analysis of 985 Cases of Rheumatic Fever and Rheumatic Carditis in Children for 10 Years(1978~1987) in Korea.
Sung Ho Cha, Sang Young Jeong, Du Bong Lee, Kyong Su Lee, Sang Bum Lee, Tae Chan Kwon, Young Chang Tockgo, Chang Sung Sohn, Keun Chan Sohn, Young Jin Hong, Chan Young Kim, Chang Yee Hong, Yong Soo Yun, Jung Yun Choi, Chang Hwi Kim, Chul Ho Kim, Tae Ju Hwang, Jae Suk Ma, Chan Uhul Joo, Kyoo Hwan Rhee, Hahng Lee
Clin Exp Pediatr. 1989;32(12):1621-1631.   Published online December 31, 1989
Acute rheumatic fever and rheumatic carditis were still important disease of the acquired heart disease in children and adults, in spite of improving socioeconomic status in Korea. Recently, many outbreaks of acute rheumatic fever have been reported in the papers from developed countries. We should be aware of such outbreaks of acute rheumatic fever and should pay attention to their treatment of the patients...
A Clinical Observation on Infective Endocarditis in Childhood.
Kyung Ae Yoon, Hoan Jong Lee, Young Yull Koh, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1989;32(1):11-19.   Published online January 31, 1989
Fifty.Six cases with infective endocarditis who were admitted to Department of Pediatrics, Seoul National University Hospital from January 1979 to December 1986 were reviewed. All the cases were confirmed bγ clinical findings, blood culture and echocardiographic findings. The incidence of infective endocarditis was 0.25/ 1,000 admissions. Male to female ratio was 1.2:1. All the cases had heart defect that was congenital heart disease in...
Treatment of Acute Myelogenous Leukemia in Children: Remission Induction with Adriamycin and Cytosine Arabinoside, and Postremission Maintenance Chemotherapy with Adriamycin, Cytosine Arabinoside and 6-thioguanine.
Soon Ki Kim, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1988;31(7):850-862.   Published online July 31, 1988
The authers assessed the effectiveness of chemotherapy in 40 children with AML, experienced at Seoul National University Children’s Hospital during 8 years 5 months from April 1979 to August 1987. Remission induction treatment included adriamycin 30 mg/m2/day IV on days 1-3 and cytosine arabinoside 75 mg/m2/day continuous IV infusion on days 1-5. This regimen was repeated, if necessary, for one or two more courses. After...
A Clinical Observation on the Incidence of Childhood Leukemia.
Hyo Seop Ahn, Il Soo Ha, Soon Ki Kim, Hoan Jong Lee, Chang Yee Hong
Clin Exp Pediatr. 1988;31(7):841-849.   Published online July 31, 1988
We have analysed the type, age, sex, initial hematologic values and cell markers in 295 children, who had been diagnosed as leukemia at the department of pediatrics, Seoul National University Hospital, from Jan. 1983 to Dec. 1987. The patients were composed of 197 cases (66.8%) of ALL, 82 cases (27.7%) of ANLL and 16 cases (5.5%) of CML. FAB subclassification have been done in...
Study on Diagnostic Methods for Spleen in Complex Heart Disease.
Jung Yun Choi, Yong Soo Yun, Chung Il Noh, Chang Yee Hong, Kyung Mo Yeon, In One Kim
Clin Exp Pediatr. 1988;31(7):833-840.   Published online July 31, 1988
Thirty one cases of congenital heart disease with suspicious splenic anomaly were prospectively studied at Seoul National University Children’s Hopsital from October, 1986 to February, 1988 in order to determine the sensitivity and the specificity of various non-invasive diagnostic methods for splenic status. In most cases, splenic status was confirmed by abdominal aortography. Each case had chest X-ray, abdominal X-ray, bronchus tomography, electrocardiogram, echocardiography,...
Percutaneous Transluminal Balloon Valvuloplasty for Congenital Pulmonary Valve Stenosis.
Heung Jae Lee, Jae Kon Ko, Woong Heum Kim, Nam Su Kim, Chang yee Hong
Clin Exp Pediatr. 1988;31(7):822-832.   Published online July 31, 1988
During the period of 2 years, between January 1986 and December 1987, 36 patients, aged 2 years to 18 years, with congenital pulmonary valve stenosis(PVS) (with peak systolic transvalvar gradient over 30 mmHg) underwent percutaneous transluminal balloon valvuloplasty(TBV) at Sejong General Hospital m Korea. Of a group of 36 patients, 26 were treated successfully by the conventional balloon valve dilatation technique, and 6 were treated...
Percutaneous Balloon Angioplasty in Patients with Congenital Aortic Valvular Stenosis.
Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1988;31(7):817-821.   Published online July 31, 1988
Aortic valve stenosis was relieved by balloon dilatation during cardiac catheterization on 9 children aged 1 month to 15 years. Aortic valve diameter was estimated by two dimensional echocardiography to assist in the choice of balloon size. Before dilatation the transaortic systolic pressure gradients ranged from 60 mmHg to 177 mmHg, (mean: 91 ±38 mmHg). There were signifeant reduction in the transaortic systolic pressure...
Endodermal Sinus Tumor in Children.
Jae Sun Jung, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1988;31(6):772-778.   Published online June 30, 1988
Thirty-three cases of endodermal sinus tumor were reviewed. They were diagnosed at Seoul National University Hospital over the last 9 years. Sixteen were testicular, 12 were sacrococcygeal and the others were mediastinal, vaginal, ovarian, retrovesical and tongue endodermal sinus tumor. Endodermal sinus tumor of the tongue was the first reported case in the world. Serum 公-fetoprotein of 32 cases was elevated at diagnosis and...
Burkitt Lymphoma in Children.
Soo Jong Hong, Dong Kyu Jin, Hee Young Shin, Hyo Seop Ahn, Chang Yee Hong, Je G Chi
Clin Exp Pediatr. 1988;31(4):482-491.   Published online April 30, 1988
Seventeen cases of Burkitt lymphoma under 15 years of age who were admitted to Dept, of Ped., Seoul National University Hospital from Jan. 1979 to Dec. 1986 were reviewed and analysed. One hundred and six cases of non-Hodgkin lymphoma were seen during the same period. 1) Burkitt lymphoma accounted for 16% of non-Hodgkin lymphoma. 2) The age ranged from 10/12 year to 15 5/12 years, with...
Acute Tumor Lysis Syndrome in Burkitt Lymphoma.
Dong Kyu Jin, Soo Jong Hong, Il Soo Ha, Hyo Seop Ahn, Yong Choi, Chang Yee Hong
Clin Exp Pediatr. 1988;31(3):362-369.   Published online March 31, 1988
To assess the tumor lysis syndrome in Burkitt lymphoma, we analyzed the clinical and laboratory findings of 17 patients with Burkitt lymphoma who were admitted to the Department of Pediatrics, Seoul National University Hospital from January 1979 to December 1986. The acute tumor lysis syndrome was diagnosed when two of the five following metabolic abnormal- ities were met: ① hyperuricemia (≥8.0mg/dl), ② hyperphosphatemia (≥5.5 mg/dl),...
Estimation of Pressure Difference Between Right and Left Ventricle in Ventricular Septal Defect with Doppler Echocardiography.
Myung Chul Cho, Byung Kiu Park, Woo Sung Park, Chung Il Noh, Jung Yun Choi, Yong Soo Yoon, Chang Yee Hong
Clin Exp Pediatr. 1988;31(3):315-321.   Published online March 31, 1988
We compared the interventricular pressure gradient with Doppler echocardiography and that measured during cardiac catheterization in 48 children who were admitted for diagnostic cardiac catheterization and angiography to the ward of Pediatrics, Seoul National University Children’s Hospital during the period of 7 months from June to December 1986. Among 48 cases of simple ventricular septal defect, 21 cases were supracristal (type I), and 27...
High-Dose Cytosine Arabinoside (HD Ara-C) Therapy for Refractory Acute Leukemia in Children.
Il Soo Ha, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1988;31(10):1328-1337.   Published online October 31, 1988
Eleven children with refractory acute leukemia were treated with high dose cytosine arabinoside (HD Ara-C), given at a dosage of 3 gm/m2 intravenously over about one hour every 12 hours for four to eight doses. The antileukemic effects were evaluable in nine of the patients, two with ALL, seven with ANLL. Six of the seven patients with ANLL attained complete remission, while neither...
Clinical Observation on Splenectomized Children.
Mi Ryung Um, Jae Won Song, Yong Yull Koh, Jeong Kee Seo, Hyo Seop Ahn, Chang Yee Hong, Kwi Won Park
Clin Exp Pediatr. 1987;30(5):511-517.   Published online May 31, 1987
A clinical study was performed on 26 cases of splenectomized children who had been seen at the Department of Pediatrics, Seoul National University Hospital, during the period of 7 years 7 months from January 1978 to July 1985. The results were as follows: 1) Primary diseases were hereditary spherocytosis (8 cases), Hodgkin disease for staging laparotomy (8 cases), ...
Percutaneous Transluminal Angioplasty in Four Children with Takayasu's Arteritis.
Byung Kiu Park, Sejung Sohn, Chung Il Noh, Young Soo Yun, Chang Yee Hong, Kyung Mo Yeon, In One Kim
Clin Exp Pediatr. 1987;30(4):441-449.   Published online April 30, 1987
Percutaneous transluminal angioplasty (PT A) was done in four children with Takayasu’s arteritis at Seoul National University Children’s Hospital in 1986. Successful results were obtained in all cases. But one child with narrowing of the innominate artery, thoracic aorta and occlusion of the left subclavian artery showed the most dramatic improvement clinically as well as radiologically because the lesions were focal. PT A is...
Clinical Study on the Hypoplastic Right Heart Syndrome.
Sejung Sohn, Soon Ung Kang, Chung Il Noh, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong, Dug Ha Kim, Jong Lin Rhi
Clin Exp Pediatr. 1987;30(3):281-290.   Published online March 31, 1987
A clinical observation was made on 12 cases of the hypoplastic right heart syndrome who were admitted to the department of Pediatrics, Seoul National University Hospital from January 1978 to May 1986. The -results were as follows; 1) The ratio of female to male was 1:1 and, according to the anatomic classification by Khoury, 6 cases were in type 1, 4 cases in type II...
Percutaneous Balloon Angioplasty in Children with Pulmonary Valvular Stenosis.
Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1987;30(12):1355-1362.   Published online December 31, 1987
Pulmonary valve stenosis was relieved by balloon dilatation during cardiac catheterization on 58 children aged 8 months to 15 years, mean 6.2 years. Pulmonary valve diameter was estimated by two-dimensional echocardiogrphy to assist in the choice of balloon size. Before dilatation the transpulmonary systolic pressure gradients ranged from 15 mmHg to 250 mmHg. There were significant reduction in the transpulmonary systolic pressure gradients immediately after...
Clinical Observation of Truncus Arteriosus.
Sang Kyu Park, Young Soo Kim, Sejung Sohn, Chung Il Noh, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1987;30(1):45-54.   Published online January 31, 1987
This is the report on 10 cases of truncus arteriosus, experienced at the Seoul National University Hospital, during past 7 years from Jan. 1979 to Dec. 1985. The results of observations were as follows; 1) There were 6 males and 4 females, and according to Collett and Edwards’ classification, 5 cases were in type 1, 4 case were in type II and 1 case...
Clinical Studies on Ventricular Septal Defect with Septal Aneurysm.
Jae Kon Ko, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong, Kyung Mo Yeon
Clin Exp Pediatr. 1986;29(5):504-509.   Published online May 31, 1986
Ninety-nine cases of ventricular septal defect with septal aneurysm which were confirmed by angiocardiography and 2-D echocardiography during the period of 2 years from 1983 to 1984 at SNUH were studied and analyzed. The summary of the findings are as follows: 1) Septal aneurysm was found in 99(26.9%) of 368 cases of total VSD and in 38.2% among membranous VSD....
Renovascular Hypertension in Childhood.
Jae Won Song, Soo Heun Lim, Yong Choi, Kwang Wook Ko, Chang Yee Hong, Kyung Mo Yeon
Clin Exp Pediatr. 1986;29(4):381-386.   Published online April 30, 1986
The following results were obtained from a retrospective analysis of 21 cases of renovascular hypertension who were admitted to Pediatric Department, Seoul National University Hospital, during the period from January 1978 to December 1985. 1) Takayasu arteritis was the most common cause (15 out of 21, 71%), and fibromuscular dysplasia of renal artery was confirmed only in two (9.5%) cases. 2) Male...
Clinical Studies on Congenitally Corrected Transposition of the Great Arteries.
Byong Kwan Son, Chung Il Noh, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1986;29(3):287-295.   Published online March 31, 1986
The clinical studies were performed on 29 congenitally corrected transposition of£the great arteries (C-TGA) confirmed by cardiac catheterization and angiocardiography at the Department of Pediatrics, Seoul National University Hospital, from Oct. 1957 to Dec. 1984. The results are as follows; 1) There were 29 cases of C-TGA, representing 0.7% of a total of 4,096 CHD patients. The male: female ratio was 3.1 :...
Cardiac Malposition.
Sejung Sohn, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong, Je G Chi
Clin Exp Pediatr. 1986;29(2):186-202.   Published online February 28, 1986
Cardiac malposition refers to any position of the heart other than a left-sided heart in a situs solitus individual. Authors analyzed the clinical, radiological, operative and autopsy findings of 69 patients with cardiac malpositions by segmental approach to describe the internal cardiac anatomy and their arterial connections. 1) Male to female sex ratio was 1.23 : 1 and 68% of cases were under...
Case Report
Hodgkin’s Disease in Children
Soo Jong Hong, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1986;29(12):1352-1359.   Published online December 31, 1986
Twenty one cases of Hodgkin’s disease under 15 years of age who were admitted to Dept, of Ped. of Seoul National University Hospital from Jan. 1976 to Dec. 1985 were reviewed and analysed. One hundred and five cases of non-Hodgkin’s lymphoma were seen during the same period. 1) The ratio of non-Hodgkin’s lymphoma to Hodgkin's disease was 5:1. 2) The age ranged from 18/12 years...
A Case of Chronic Myelogenous Leukemia in a Child Treated in a Interferon.
Ill Soo Ha, Jon Lin Rhi, Se Jung Sohn, Dug Ha Kim, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1986;29(11):1232-1238.   Published online November 30, 1986
A child with Ph^positive chronic myelogenous leukemia was treated with human leukocyte interferon (Hu IFN-alpha). Hematologic remission was obtained in 16 weeks of treatment, and white blood cell count was decreased in number from 115,000 to 9,600. Platelet:count, spleen size, LDH and bone marrow M/E ratio were decreased in parallel, but there was no significant change in serum vitamin B12...
Original Article
Heart Diseases in Korean Children: Past and Present.
Chang Yee Hong
Clin Exp Pediatr. 1986;29(11):1161-1167.   Published online November 30, 1986
Bone Marrow Cell Culture(GM-CFU) in Anaplastic Anemia of Children.
Jae Sun Jung, Chang Yee Hong
Clin Exp Pediatr. 1985;28(9):888-898.   Published online September 30, 1985
Bone marrow cell cultures (GM-CFU) were performed in the 15 cases of children with aplastic anemia and the correlation with the clinical course were investigated. They have been treated with androgen with or without low dose prednisone and supportive care. Bone marrow cell cultures from 8 children without any evidence of aplastic anemia were performed as a control. 1)In control...
Left Ventricular Function in Chronic Severe Anemia by Echocardiographic Study.
Jae Kon Ko, Chang Yee Hong
Clin Exp Pediatr. 1985;28(9):880-887.   Published online September 30, 1985
It is well known that chronic anemia is associated with hemodynamic alterations like increased cardiac output and stroke volume and decreased peripheral vascular resistance. Left ventricular size and function were studied by echocardiography in 16 chronic anemia patients, mainly aplastic anemia, without evidence of cardiac decompensation. Left ventricular dimension, stroke volume, ejection fraction and fractional shortening were calculated. The LV...
Case Report
Three Cases of Congenital Hypoplastic Anemia.
Heui Jeong Kwon, Myung Hyun Lee, Jung Hwan Choi, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1985;28(8):829-835.   Published online August 31, 1985
Congenital hypoplastic anemia is a rare disease characterized by aplasia or severe hypoplasia of the erythron, with onset usually at birth or during early infancy. This report presented three cases of congenital hypoplastic anemia in 3 infants with pallor and irritability which were noticed since one to three months of age. Three cases were treatsd with prednisolone and the courses of...
Original Article
A Clinical Study on Cardiofacial Syndrome (Asymmetric Cry Syndrome).
Chung Il Noh, Chang Yee Hong
Clin Exp Pediatr. 1985;28(7):637-641.   Published online July 31, 1985
Seven patients with cardiofacial syndrome were observed for twenty months from Oct. 1983 to May. 1985 at the Pediatric Department of Seoul National University. Age ranged from 1 months to 10 years and six patients were male. Right-sided facial palsy occurred in 4 patients and left-sided in 3 patients. Cardiac defects were TOF, VSD(membranous), Criss-Cross heart with large VSD, pulmonary...
Comparative Study on Quantitation of Left to Right Shunts in Ventricular Septal Defect Using Oximetry and Radionuclide Method.
Chang Yee Hong, Jung Yun Choi, Se Won Park, Yong Soo Yun, Chang Soon Koh
Clin Exp Pediatr. 1985;28(4):340-344.   Published online April 30, 1985
In 80 children with isolated ventricular septal defect, quantitation of left to right shunts was performed using oximetry and rdionuclide angiocardiography(RNA). The radionuclide angiocardiograms were acquired and analized by a gamma camera interfaced to a digital computer system. Pulmonary to systemic f!ow(Qp/Qs) ratios were calculated by analysis of pulmonary time-activity histograms using a gamma variate model. A comparison of the...
Heart Disease Screening for Primary School Children.
Chang Yee Hong, In Sil Lee, Hee Ju Kim, Jung Hwan Choi, Hae Il Cheong, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1985;28(3):258-262.   Published online March 31, 1985
A heart disease screening program was performed on 15,685 primary school children in Seoul City from the first to sixth grade to estimate the prevalence of heart diseases. Among the 15,685 children examined, 45 were confirmed to have heart disease (2.9/1,000) Out of the 45 children, 38 had congenital heart disease(2.4/1,000) and 7 had rheumatic heart disease(0.4/1,000) and the ratio...
Captopril in Children with Renovacular Hypertension.
Yong Choi, Hoan Jong Lee, Hee Young Shin, Kwang Wook Ko, Chang Yee Hong
Clin Exp Pediatr. 1985;28(1):58-67.   Published online January 31, 1985
Captopril, a kind of converting enzyme inhibitors, is a promising anti-hypertensive drug, which is developed recently, and studied mainly in adult patients. We administered captopril to 4 children with renovascular hypertension, three of them accompanied Takayasu's arteritis and the remainder had isolated lesion. Three to five times of initial trials were performed on each patient with 12.5 mg of captopril....
Case Report
A Case of Isolated Congenital Tricuspid Insufficiency.
Dong Hyun Choo, Dong Kyoon Kim, Jung Yeon Choi, Yong Soo Yoon, Chang Yee Hong
Clin Exp Pediatr. 1984;27(8):814-819.   Published online August 31, 1984
Isolated congenital tricuspid insufficiency is a rare anomaly and may be caused by abnormal chordae tendinae, papillary muscle, or valve leaflets. The cause of these lesions is generally ascribed to incomplete undermining of primitive endocardial cushion by sinusoidal space, which differentiate the cushion into the various valvular structures. Carvallo’s sign, most characteristic clinical sign in tricuspid insufficiency, is augumentation of systolic...
Original Article
Clinical Study of Wilms' Tumor .
Myung Hyun Lee, In Sil Lee, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1984;27(6):603-609.   Published online June 30, 1984
Thirty-five cases of Wilms tumor treated at the Seoul National University Hospital from 1969 to 1983, were analyzed and the results are as follows: 1)Ages at nephrectomy were from 1 monh. to 11 years and 8 months. The mean, age was 3 years and 4 months and the median was 2 years and 9 months. The sex ratio of male...
Case Report
Two Cases of Anomalous Origin of the Right Pulmonary artery from the Ascending Aorta.
Kyu Gap Hwang, Gu Soo Kim, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1984;27(5):501-505.   Published online May 31, 1984
Anomalous origin of one pulmonary artery from the ascending aorta is a rare congenital malformation. It happens as the result of abnormal development of the 6th aortic arch. Anomalous origin of right pulmnary artery is more frequent than left. It is frequently associated with P.D.A., V.S.D. and T.O.F. In this malformation, congestive heart failure develops in early life and once the...
Three Cases of Idiopathic Hypertrophic Subaortic Stenosis.
Sei Weon Yang, Dong Gyoon Kim, Jong Jin Seo, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1984;27(5):493-500.   Published online May 31, 1984
Idiopathic Hypertrophic Subaortic Stenosis is a primary disease of cardiac muscle that is probably congenital, is often genetically transmitted, and is characterized by asymmetric septal hypertrophy, systolic anterior motion of anterior mitral valve and disorganization of cardiac muscle cells. The authors experienced 3 cases of Idiopathic Hypertrophic Subaortic Stenosis which were confirmed by echocardiography, cardiac catheterization and angiocardiography. The literatures...
A Case Report of Double Outlet Right Ventricle(S.D.L.) with Subpulmonic Ventricular Septal Defect and Pulmonary Stenosis.
Jae Sun Jung, Sun Ok Park, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1984;27(4):407-412.   Published online April 30, 1984
Among the double outlet right ventricle, S.D.L. type with subpulmonic ventricular septal defect is extremely rare. We experienced 10 year old girl who had S.D.L. type of double outlet right ventricle with subpulmonic mitral valvular insufficiency and LV-RA canal. The literature were reviewed.
Original Article
Clinical Observation of Acute Lymphocytic Leukemia with Mediastinal Mass.
In Sil Lee, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1984;27(4):343-349.   Published online April 30, 1984
Twenty four cases of acute lymphocytic leukemia with mediastinal mass were studied at the Department of Pediatrics, Seoul National University Hospital from September 1965 to August 1983. Analysis were done with regard, to age, sex, chief complaints, organ size (liver, spleen and lymph nodes), initial hemoglobin, white blood cell and platelet count, initial bone marrow findings and lymphoblast surface markers....
Case Report
Four Cases of Papillary Thyroid Cancer in Childhood.
Sei Weon Yang, Sei Won Park, In Sil Lee, Hyo Seup Ahn, Hyung Ro Moon, Chang Yee Hong, Kwi Won Park, Je Geun Chi
Clin Exp Pediatr. 1984;27(3):282-287.   Published online March 31, 1984
Papaillary thyroid cancer is a rare lesion in children. It progresses slowly and its prognosis is relatively good. A painless nodule in the thyroid or in the neck is the usual first evidence of disease. Cervical lymph node involvement is usually present at the time of the initial diagnosis and is often bilateral. The lungs are the most common site...
A Case of Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery.
Young Seo Park, Gu Soo Kim, Jung Yeon Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1984;27(3):277-281.   Published online March 31, 1984
The anomalous origin of the left coronary from the pulmonary artery is a rare congenital cardiac anomaly and there has been no case reported in Korea. We report one case of the anomalous origin of the left coronary artery from the pulmonary artery. He was an 11 month-old male body, who was suffered from congestive heart failure since 5 months of...
A Case of Supravalvular Stenotic Ring of the Left Atrium associated with VSD and PDA.
Chung Il Noh, Jung Yun Choi, Yong Soo Yoon, Chang Yee Hong, Kyung Mo Yeon, Joon Ryang Rho
Clin Exp Pediatr. 1984;27(2):184-190.   Published online February 28, 1984
Supravalvular stenotic ring of the left atrium is one of the rare anomalies, which is usually accompanied by other cardiac defects. It is very important to recognize its existence earlier and preoperatively. Main tools in. diagnosis are angiocardiography and echocardiography. We have experienced a patient with supravalvular stenotic ring of the left atrium with coexisted with VSD and PDA. M-mode...
Original Article
Cardiac Involvement of Kawasaki Disease.
Gu Soo Kim, Kyu Gap Hwang, Byung Kwan Sohn, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1984;27(2):135-145.   Published online February 28, 1984
Twenty-nine cases of Kawasaki disease, who were admitted to the Dept, of Pediatrics, Seoul National University Hospital, were evaluated on the incidence, clinical signs and laboratory findings of cardiovascular system. Among them two patients were excluded from the incidence of cardiac involvement: One with incomplete study died at home on 22nd day after the onset, and the other was referred because...
Absence of Inferior Vena Cava.
Sun Oak Park, Chang Yee Hong
Clin Exp Pediatr. 1983;26(8):760-769.   Published online August 31, 1983
Out of 1617 cases of congenital heart disease, who were admitted to the Pediatric ward, Seoul National University Hospital, for cardiac catheterization during recent 5 years, 20 patients with anomalous inferior vena cava were observed. Associated cardiac and extracardiac vascular anomalies were reviewed. Cardiac and visceral malposition were also analyzed. Results; 1) Incidence was 1.2% of total 1617 catheterized patients. 2) Male and female...
Clinical Observation of Tricuspid Atresia.
Myung Hyun Lee, Yong Soo Yoon, Chang Yee Hong
Clin Exp Pediatr. 1983;26(8):751-759.   Published online August 31, 1983
Twenty one cases of triciispid atresia which were diagnosed at the department of Pediatrics, Seoul National University Hospital during past twelve years and eleven months were reviewed and analysed. The results were as follows. 1) There were 8 males and 13 females. According to anatomical classification, 15 cases were in type 1, 4 cases in type 표 and 2 cases in type...
Supracristal Ventricular Suptal Defect in Korean.
Hee Ju Kim, Son Moon Shin, Yong Soo Yoon, Chang Yee Hong, Yung Kyoon Lee
Clin Exp Pediatr. 1983;26(7):631-639.   Published online July 31, 1983
Supracristal ventricular septal defect has engendered an interest in recent years because of the racial difference in its incidence and the unusually high association of the aortic valve abnormalities. The relative incidence of supracristal ventricular septal defect was studied in Korean. During the period of eight years from January 1974 to December 1981, 119 cases(27.6%) of supracristal type were noted among 431 cases of...
A Study on Frequency of Malignant Tumors in Children.
Chang Yee Hong, Hyo Seop Ahn, Byung Kwan Sohn, Son Moon Shin, In Sil Lee
Clin Exp Pediatr. 1983;26(5):489-498.   Published online May 31, 1983
Five hundred and thirty-nine cases of malignant tumors (excluding leukemia) under 15 years of age who were admitted to Seoul National University Hospital from January 1967 to December 1981 were reviewed and analysed. Three hundred and ninety-nine cases of leukemia were seen during the same period and total 938 cases of malignancies including leukemia were observed. 1. The frequency of malignant tumors...
Case Report
A Case Report Kostmann Syndrome.
Han Wook Yoo, Son Moon Shin, Hyo Seop Ahn, Yong Choi, Chang Yee Hong
Clin Exp Pediatr. 1983;26(3):284-288.   Published online March 31, 1983
Kostmann syndrome (Infantile genetic agranulocytosis), a disease characterized by recurrent infections leading to death in infancy, shows an agranulocytosis with variable monocytosis, eosinophilia in the peripheral blood, accompanied by the maturation arrest of the myelocytic series at the promyelocyte-myelocyte level. A 2 years 3 month old female patient with Kostmann syndrome is reported, who has suffered from recurrent infections since 1 month of age. During...
Original Article
Clinical Study on the Dilated Cardiomyopathy in Children.
Jong Jin Seo, Byong Gwan Sohn, Jung Yeun Choi, Yong Soo Yoon, Chang Yee Hong
Clin Exp Pediatr. 1983;26(11):1081-1094.   Published online November 30, 1983
Forty five cases of dilated cardiomyopathy who were admitted, to Seoul National University Hospital from June, 1980 to May, 1983 were studied on the clinical features and laboratory findings. 1) Twenty two cases (44.4%) were primary dilated cardiomyopathy, and the other 25 case (55.6%) were secondary. Nineteen cas&s(95.0%) of primary dilated cardiomyopathy were diagnosed within 3 year of age, but sacondary dilated cardiomyopathy did...
A Clinical Study of Cor Triatriatriatum.
Jae Ho Lee, Il Suck Chang, Nam Su Kim, Yong Soo Yoon, Chang Yee Hong
Clin Exp Pediatr. 1983;26(11):1070-1080.   Published online November 30, 1983
Cor triatriatum is a rare congenital cardiac anomaly in which the left atrium is divided into two chambers by an abnormal fibro-muscular septum with, a small opening or not, product pulmonary venous obstruction and pulmonary hypertension. Three cases of cor triatriatum were observed at the Dept, of Pediatrics, Seoul National University. Each patient had no specific problem during early infancy, and presented...
Case Report
A Case of Trensient Myeloproliferative Disorder with Down Syndrome.
Dong Gyoon Kim, Jae Ho Lee, Jung Il Noh, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1983;26(10):1024-1028.   Published online October 31, 1983
Transient myeloproliferative disorder has been reported in infants with Down syndrome. Infants with Down syndrome and this transient myeloproliferative disorder often present with signs and symptoms that are clinically and hematologically indistinguishable from congenital acute myelogenous leukemia. In contrast to congenital AML, complete clinical and hematological recovery occurs within weeks to months of diagnosis without any specific anti- leukemic treatment. A case of transient myeloproliferative disorder...
Original Article
Clinical Observation of Double Outlet Right Ventricle.
In Suck Seo, Yong Soo Yoon, Chang Yee Hong
Clin Exp Pediatr. 1982;25(8):769-780.   Published online August 31, 1982
Eighteen cases of double outlet right ventricle were observed during past six years at the department of pediatrics, Seoul National University Hospital. 1. Therw were 13males and 5 females. Sex ratio showed male predominance with the ratio of 2, 6:1. 2. According to the Sondheimer's classification, 6 cases were in group l, none in group ll, 10cases in group lll...
Case Report
Aneurysm of the Main Pulmonary Artery-Report of a case and review of the literature.
Eue Cho Yang, Eung Sang Choi, Yong Soo Yoon, Chang Yee Hong, Joon Ryang Roh, Kyung Mo Yeon
Clin Exp Pediatr. 1982;25(2):162-167.   Published online February 28, 1982
Pulmonary artery aneurysms are extremely rate and are seldom diagnosed during life. In true aneurysms, dilatation tends to be confined to the main trunk of the artery and degenerative changes in the wall are found. In 1971, Williams et al reported the first successful excision and replacement of the main pulmonary artery, including the bifurcation, with a dacron graft. Since...
Original Article
Pericardial Effusion in Patients with Rheumatic Fever.
In Suck Seo, Hee Ju Kim, Jae Ho Lee, Yong Soo Yoon, Yong Choi, Chang Yee Hong
Clin Exp Pediatr. 1982;25(12):1225-1233.   Published online December 31, 1982
Pericarditis denotes worse prognosis in patients with rheumatic fever. During the period of 4 years from Jan. 1978 to Dec. 1981, one hundred and eighteen patients were diagnosed as rheumatic fever on the basis of revised Jones* criteria. One hundred and one patients of them were evaluated with M-mode echocardiography, and were analysed according to Horo- witz^ classification of pericardial effusion. The results were as...
Clinical Studies on Total Anomalous Pulmonary Venous Connection.
Young Jin Hong, Kee Hong Kwon, Hae Il Cheong, Jung Yeun Choi, Yong Soo Yoon, Chang Yee Hong
Clin Exp Pediatr. 1982;25(11):1120-1130.   Published online November 30, 1982
Total anomalous pulmonary venous connection (TAPVC) is a rare congenital defect in which all the pulmonary veins are connected to the right atrium or its tributary veins. Without surgical intervention, most patients with TAP VC have grave prognosis, with cardiac failure and death in infancy. But owing to the advances of surgical technique and postoperative care, complete correction has been accomplished with good results. Sixteen...
Shigelle, and Salmonella.
NamSu Kim, Jae Ho Lee, Chang Yee Hong
Clin Exp Pediatr. 1982;25(11):1106-1119.   Published online November 30, 1982
1. A total of 3,178 strains of Staphylococcus aureus, 278 strains of Shegella and 506 strains of Salmonella were isolated and tested for sensitivity against antimicrobial agents at Seoul National University Hospital from January 1971 to December 1980. Clinical study was made on children under 15 years old. 2. Sensitive strains to antimicrobial agents were more frequently isolated in children than adult. But the pa竹ern of sensitivity...
Testicular Leukemia.
Young Jin Hong, Jung Yeun Choi, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1982;25(1):29-35.   Published online January 31, 1982
Leukemic infiltration of the testes has been relatively rare disease. But increased survival due to advance in the treatment of childhood leukemia has been associated with an increase in incidence of leukemic infiltration of the tests. Six of 66 male children with acute lymphocytic leukemia and 2 of 2 male children with leukemic transformation on non-Hodgkin's lymphoma, who have been...
Clinical Observation on Factors Influencing Survival in Pediatric Acute Lymphocytic Leukemia.
Chang Yee Hong, Jung Yeun Choi, Hyo Seop Ahn
Clin Exp Pediatr. 1982;25(1):8-18.   Published online January 31, 1982
Sixty two properly treated acute lymphocytic leukemia cases who were diagnosed at SNUH, from 1958 to July, 1981 were studied. Among them, 20 cases had survived more than 3 years and 42 cases survived less than 3 years. The 11 cases of 20 are now alive and off theray and the remainder 9 cases were expired after survival for more...
Treatment of Aplastic Anemia with Lithium Carbonate.
Chang Yee Hong, Hyo Seop Ahn
Clin Exp Pediatr. 1981;24(7):620-624.   Published online July 15, 1981
The effect of lithium carbonate was investigated on the five cases of aplastic anemia with measuring of serum level and EKG check. Reticulocyte count increased slightly only in one case. Hemoglobin, WBC and platelet count did not show any significant increase in all cases. No apparent side effect, including EKG finding, was observed.
Case Report
Fanconi Anemia.
Sang Il Lee, Young Yul Koh, Jung Gi Suh, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1981;24(2):153-163.   Published online February 15, 1981
Five cases of Fanconi anemia were observed during these 7 *years. It acounts for about 6.7% of the total 75 aplastic anemia seen during those same period in SNUH. Three were boys and two were girls. The initial symptom was nasal bleeding or pallor which observed between the age of 2 years and 6 years. They all revealed growth retardation...
Original Article
Histiocytic Medullary Reticulosis in Children: Report of Four Cases and Analysis of Previously Reported Cases.
Eue Cho Yang, Jae Ho Lee, Soon Ung Kang, Hyo Seop Ahn, Chang Yee Hong, Je G Chi, Yong Il Kim
Clin Exp Pediatr. 1981;24(10):928-941.   Published online October 15, 1981
Histiocytic Medullary Reticulosis(H.M.R.) is a rapidly progressing fatal disease seen most often in adults, but it has been reported in children younger than 15 years of age. H.M.R. is clinically characterized by fever, wasting generalized lymphadenopathy and hepatosplenomegaly. In the terminal stage, jaundice, purpura, anemia and pancytopenia are all present with or without skin involvement. Cardinal pathologic features are systemized...
Case Report
A case of Right Atrial Myxoma.
Kyoo Duck Lee, Youn soo Yoon, chang Yee Hong
Clin Exp Pediatr. 1980;23(5):391-395.   Published online May 15, 1980
Right atrial myxoma is a rare primay intra cardiac tumor and it presents various clinical manifestations mimicking Tricuspid stenosis, Constricive Pericarditis, and Subacute Bacte rial Endocarditis A 10 years old boy with exertioal dysyonea and general weakness for 40days was admitted to our hospital under the impressionof right atrial myxoma.clincal diagnosis was made by echocardiogram, cardiac catheterization and right artiograhpy...
Cardiac Valve Replacement in the Pediatric Age.
Yong Jin Kim, Chang Yee Hong, Yung Kyoon Lee
Clin Exp Pediatr. 1980;23(3):246-251.   Published online March 15, 1980
Replacement of cardiac valves in the pediatric patients is infrequent compared with in adult for the treatment of diseased heart valve. Furthermore, uncertainties regarding the long term fate of prosthetic value and effects of a fixed-orifice walve in the growing children are the main concern in pedriatric patients. Between January 1974 and October 1979, in 10 children, 15years or younger,...
Original Article
Results of Sereening Examination On Children for Adoption.
Chang Yee Hong
Clin Exp Pediatr. 1980;23(3):198-203.   Published online March 15, 1980
Pre-adoption screening examination was performed on 1257 infants and children. Routine physical examination and laboratary examination(urinalysis, blood examination, Tb skin test, VDRL, PKU and chest X-ray on children older than 2 years of age) were done. Further laboratory examinations were performen on the children with abnormal findings by the first screening. The results were as following. 1. Sex: Girls were...
Case Report
Gentamicin-resistant Pseudonomas Aeruginosa Menigitis.
Chung Il Noh, Yong Soo Yoon, Hyung Ro Moon, Chang Yee Hong
Clin Exp Pediatr. 1979;22(7):525-531.   Published online July 15, 1979
We have treated 4-year-old with amikacin and rifampin, who suffered from bacterial meningitis due to gentamicin-resistant Pseudomonas aeruginosa. There was no complication during treatment. Even though we didint check audiometry and BUN and/or creatinine, urinalysis was normal and physical examination revealed no abnormalities. He had been treated fora about 3 months with various antibiotics including gentamicin, intravascular and intrathecal, and...
Original Article
Immunity to Diphetheria in Korean Children by means of Schick Test.
Chung Il Noh, Chang Yee Hong
Clin Exp Pediatr. 1979;22(11):940-946.   Published online November 15, 1979
In spite of prevalence of diphtheria, there were scant reports about immunity to diphtheria Korea. The Schick tests were done in the admitted patients to the pediatric department of the SUNH and in the children at the Bupyung area. Among the total children, 22.5% were Schick-positive. The positive rate of the patients of SUNH is 19.7%, which is different form...
The Electrocardiographic and Vectorcardiographic Findings of Tetralogy of Fallot.
Chang Yee Hong, Jung Yean Choi
Clin Exp Pediatr. 1979;22(1):13-19.   Published online January 15, 1979
The electrocadiographic and vectorcardiographic findings were reviewed in 49 cases of tetralogy of Fallot, confirmed by cardiac catheterization and angiocardiographic findings and/or, by surgery. In most cases, the electrocardiographic findings were right axis deviation and right ventricular hypertrophy. Vectorcardiographic findings were as following; 1) The initial vector directed to anterior and slightly left or right. 2) The maximum vector directed...
Case Report
Malignant Choroid Plexus Tumor in an Infant.
Jung Yean choi, Bong Sik Kim, Hyo Sup Ahn, Chang Yee Hong, Je Geun Chi, Shin Kwang Khang, Kae Yong Song
Clin Exp Pediatr. 1978;21(7):552-556.   Published online July 31, 1978
A 42 day-old male infant visited to our emergency room with chief complaints of convulsion. Prenatal and birth histories were unremarkable. The patient appeared well except persistent jaundice and had no signs of increased intracranial pressure. The head circumference at birth was not measured. The head circumference at 42 days was 39cm(50th percnntile) At the age of 42 days, tonic...
Original Article
Hemodynamic Studies on Atrial Septal Defect (Secundum Type).
Chang Hyo Lce, Chang Yee Hong, Yong Kyun Lee
Clin Exp Pediatr. 1977;20(3):199-204.   Published online March 31, 1977
Observation of hemodynamic findings, E.K.G. findings and correlation between them were performed on 36 cases of atrial septal defect (secundum type) which were confirmed by cardisc catheterization and operation at the Department of Pediatrics and Chest Surgery, Seoul National University Hospital, during the past 13 years period from 1963 to 1976. The results were as follows; 1. On the E.K.G.,...
Brain Abscess in Congenital Heart Disease
Chang Yee Hong, Hyo Seop Ahn, Heung Jai Lee, Byung Kwan Son
Clin Exp Pediatr. 1976;19(12):904-914.   Published online December 31, 1976
Clinical observation was performed on 9 cases of brain abscess which were complicated with cyanotic congenital heart disease which were seen at the Department of Pediatrics, Seoul National University Hospital, during the past 19 years from 1957 to 1976. 1. During the last 19 years 1, 296 cases of [congenital heart disease were observed, and among these, 432 cases were cyanotic....
Cardiac Arrhythmias in Infants and Children
Chang Yee Hong
Clin Exp Pediatr. 1976;19(1):25-30.   Published online January 31, 1976
1.Cardiac arrhythmias which was observed during 3 years and 4 months from March 1973 to August 1975 among 2, 676 patients who visited the Department of Pediatrics and whose ECG were taken because of heart disease or suspicious heart disease were analysed. Simple sinua arrhythmias and bundle branch blocks were excluded from this study. 2. 186 cases of arrhythmis were seen...
Clinical Observation of Aplastic Anemia in Children
Chang Yee Hong, Hyo Seop Ahn, Heung Jai Lee
Clin Exp Pediatr. 1975;18(7):489-498.   Published online July 31, 1975
Clinical observation was performed on 64 cases of aplastic anemia which were seen at the Department of Pediatrics, Seoul National University Hospital, during the past 14 years 2 months period from Aug. 1960 to Oct. 1974. The results were as follows; 1.During the last 14 years 2 months, 64 cases of aplastic anemia were observed, which represents about 0.6% of...
Case Report
A Case of Takayasu’s Arteritis with Nephrotic Syndrome
Yoon Taik Kim, Kun Kil Park, Chang Yee Hong
Clin Exp Pediatr. 1974;17(5):394-398.   Published online May 31, 1974
A case of Takayasu’s arteritis with nephrotic syndrome is reported. A 6-year-old girl showed a marked hypertension with clinical manifestations of nephrotic syndrome. Aortography showed stenosis of abdominal aorta, right subclavian artery and right renal artery. A review of the literature was made.
A Case of Chronic Atrial Tachycardia
Hyo Seop Ahn, Yong Choi, Tae Woon Kim, Chong Ku Yoon, Chang Yee Hong, Johng Kun Ahn
Clin Exp Pediatr. 1974;17(2):149-153.   Published online February 28, 1974
A case of chronic atrial tachycardia in a 1 1 year and 10 month-old boy is reported. The patient was admitted with the chief complaints of palpitation and chest discomfort Tachycardia persisted till discharge but subjective symptoms were disappeared. Digitalis therapy provoked partial AV block and decreased ventricular rate. Auricular rate was also slightly decreased. The review of literature was made briefly.
Original Article
Statistical Studies on the Arm Circumference and the Skinfold Thickness in Korean Children
Chang Yee Hong
Clin Exp Pediatr. 1973;16(5):376-380.   Published online May 31, 1973
Mid-upper arm circumference and skinfold thickness (triceps, subscapular, abdominal) was measured in the 1,099 normal, well'nourished infants and children from birth to 15 years of age. These data were compared with those reported in other countries.
Clinical Trial with Sulfamethoxazole-Trimethoprim (Septrin) of Shigellosis in Children
Chang Yee Hong
Clin Exp Pediatr. 1973;16(2):137-143.   Published online February 28, 1973
Forty-two cases of shigellosis in children were treated with sulfamethoxazole-trimethoprim (Septrin) from May 1970 to October 1972. 90% of the patients showed clinical improvement within 2 days and 40 of the 42 patients (95%) within 4 days. On the 25 strains of shigellae, in-vitro sensitivity was tested against eleven antimicrobial agents. Shigella flexneri was the most frequent organism (80%). The...
Case Report
A Case of Total Anomalous Pulmonary Venous Return
Hyo Seop Ahn, Soon Young Kim, Tae Woon Kim, Jong Ku Yoon, Hyung Ro Moon, Chang Yee Hong, Hye Soon Chang, Man Cheong Han
Clin Exp Pediatr. 1973;16(2):156-160.   Published online February 28, 1973
A case of total anomalous pulmonary venous return in a 10 year and 8 month-old female was presented. The patient was admitted with the chief complaints. of palpitation and growth retardation. The diagnosis was confirmed by right heart catheterization and angiocardiography. The review of literature was made briefly.
Original Article
Erythorcyte Glucose-6-Phosphate Dehydrogenase Deficiency
Chang Yee Hong
Clin Exp Pediatr. 1972;15(6):531-533.   Published online June 30, 1972
Screening test for the red cell glucose-6-phosphate dehydrogenase deficiency was performed on 1, 027 Korean male and on 9 cases of neonatal hyperbilirubinemia and 2 cases of hemolytic anemia. No case of G-6-PD deficiency has been found in this study. According to this result G-6-PD ' deficiency is not considered to be a significant factor associated with neonatal hyperbilirubinemia in Korea while it...
Statistical Studies on Serumen Types in Koreans
Chang Yee Hong
Clin Exp Pediatr. 1972;15(6):534-536.   Published online June 30, 1972
Occurance of cerumen types was studied in 1, 271 pure Koreans and 250 orphan children including mixed-blood. The frequency of wet cerumen in pure Korean was very low and only 4. 3%. The frequency of wet cerumen in 250 orphan children in which mixed-blooded children are included was 31. 2% and 80% in 85 definite mixed-blooded children. The frequency of wet cerumen...
Meningeal Leukemia in Children: A Review of 11 Cases
Sang Woo Kim, Min Ja Pai, Ae Ra Shin, Yung Kil Chang, Chang Yee Hong
Clin Exp Pediatr. 1972;15(6):551-556.   Published online June 30, 1972
Clinical observation was made on 11 cases of meningeal leukemia out of 146 cases leukemia during 10 years from 1962 to 1971 at department of pediatrics, Seoul National University Hospital. 1. Sex ratio of male: female was 9:2. Considering the sex ratio the total leukemic children in Korea (male: female=3 : 1), the predominance in male is not significant. 2. The peak age...
Review
Pediatric Electrocardiography (V)
Chang Yee Hong
Clin Exp Pediatr. 1972;15(5):440-442.   Published online May 31, 1972
Original Article
Leukemia in Childhood with Mediastinal Masses
Min Ja Pai, Soon Young Kim, Don Hee Ahn, Chang Yee Hong
Clin Exp Pediatr. 1972;15(4):319-325.   Published online April 30, 1972
Six cases o£ acute leukemia with mediastinal masses are reported with a review of relevant literature.. Out of 105 patients wi h leukemia who had been admitted to the Department of Pediatrics, Seoul. National University Hospital for the last 6 years, six cases had huge mediastinal masses on the chest x-ray examination. In 3 of them the masses were located in the anterior...
Review
Pediatric Electrocardiography (Ⅳ)
Chang Yee Hong
Clin Exp Pediatr. 1972;15(4):343-346.   Published online April 30, 1972
Original Article
Clinical Studies on Leukemia in Childhood
Chang Yee Hong, Sang Woo Kim
Clin Exp Pediatr. 1972;15(1):10-22.   Published online January 31, 1972
One hundred and eighty-six cases of leukemia in children, aged 0〜 14 years, who were admitted Seoul Nathonal University Hospital for 15 years from Jan. 1957 to Dec. 1971, were analysed. The incidence of childhood leukemia was about 0. 3% among the total patients who visited the hospital during the same period. There were 138 boys and 48 girls (sex ratio, 2. 9...
Exophthalmos in Leukemia: A Review of 9 Cases
Jin Young Choi, Chang Yee Hong
Clin Exp Pediatr. 1970;13(2):65-70.   Published online February 28, 1970
Clinical observation was made on 9 cases of leukemia presenting exophthalmos out of 108 cases leukemia during 10 years from 1960 to 1969 at the department of pediatrics, Seoul National University Hospital 1. The incidence of exophthalmos among 108 cases of all leukemias was 8.3%, and sex ration was male/female=3. 5/1 with the age range between 9 months to 13 years,...
Paroxysmal Tachycardia in Children
Chang Yee Hong
Clin Exp Pediatr. 1968;11(9):495-498.   Published online September 30, 1968
Three cases of paroxysmal tachycardia in children which have been observed in past five years were presented and reviewed. AII of them were male and were brought to the hospital with symptoms of heart failure. The intervals between the estimated onset of the attack and the time when they were brought to the hospital were at least 4, 5. and 9 days respectively....
Review
Staphylococcal Pneumonia and Empyema in Infants and Children
Chang yee Hong
Clin Exp Pediatr. 1968;11(3):159-162.   Published online March 31, 1968
Original Article
Clinical Studies on Diphtheritic Myocarditis
Suk Chui Kang, Soon Yong Lee, Yong Kyoo Lee, Chang Yee Hong
Clin Exp Pediatr. 1968;11(1):5-12.   Published online January 31, 1968
During the 8 year period, from Jan. 1960 to Oct. 1967, 618 cases of diphtheria were admitted to the Department of Pediatrics, Seoul National University Hospital and of the total patients, 51 cases with diphtheritic myocarditis were evaluated clinically. The results were as follows: 1.The incidence of diphtheria reached its peak during winter season. The peak age distribution ranged from...
Chronic Myelocytic Leukemia in Childhood
Soon Yong Lee, Tae Sub Shim, Chang Yee Hong
Clin Exp Pediatr. 1967;10(9):487-494.   Published online September 30, 1967
Five cases of chronic myelocytic leukemia out of 96 cases of leukemia in childhood for 10 years, during January 1957 May 1967 are presented. Incidence of chronic myelocytic leukemia among 96 cases of all leukemias was 5.3% and sex ratio was male : female=2:3 with age range between 7 months~8 years of age. Chief complaints on admission were abdominal distention...
Clinical Studies on Leukemia in Childhood
Chang Yee Hong, Tae Sub Shim
Clin Exp Pediatr. 1967;10(5):261-268.   Published online May 31, 1967
Ninety cases of leukemia in children, aged 0~14 years, who were admitted Seoul National University Hospital during the period from Jan. 1957 to Dec. 1966, were analysed clinically and hematologically. The incidence of childhood leukemia was about 0.3% among the total patients who visited the hospital during the same period. There were 69 boys and 21 girls (sex ratio, 3.3:1)....
Atypical Patent Ductus Arteriosus
Young Hun Chung, Tae Sub Shim, Sung II Ahn, Chang Yee Hong
Clin Exp Pediatr. 1967;10(2):85-90.   Published online February 28, 1967
Four cases of atypical patent ductus arteriosus are presented. All of them had history of frequent upper respiratory infection and exertional dyspnea since infancy. Systolic murmurs were audible on the pulmanic area. On radiologic examination, heart was markedly enlarged, pulmonary segment was prominent and pulmonary vascular markings were increased at the proximal part. E.K.G. findings revealed high voltage of QRS...
Case Report
A Case of Hand-Schiiller.Christian Disease
Chang Soo Ra, Nam Je Im, Seung II Ahn, Chang Yee Hong
Clin Exp Pediatr. 1966;9(5):313-320.   Published online September 30, 1966
A Case of Hand-Schuller-Christian disease (2yr. 2mo. old girl) was treated with Vinblastin sulfate and steroid. No noticeable improvement was observed by the treatment with Vinblastine sulfate and the patient expired on the 85th hospital day, about 10 months after the onset.
Original Article
Studies on the Cause of Death in Orphan Infants and Children
Mahn Kyoo Yang, Koo Hyun Chung, Chang Yee Hong, On Za Kim
Clin Exp Pediatr. 1966;9(4):219-225.   Published online July 31, 1966
The spectrun of diseases and the causes of death in orphan infants are different from those in ordinary infants. Many of them have been severly malnourished already before coining to the orphanage. They are under deficient tender and care in crowded condition. It is important for a pediatrician working in orphange hospital to know the main causes of death in...
Case Report
Measles Encephalitis
Chong Koo Yun, Kyung Suk Yang, Chang Yee Hong
Clin Exp Pediatr. 1966;9(3):189-192.   Published online May 31, 1966
A case of measles encephalitis treated with steroid and gamma globulin is presented and the literature is reviewed.
Case Report
Total Anomalous Pulmonary Venous Return(A Case Report and Review of Literature)
Chang Yee Hong, Je G. Chi
Clin Exp Pediatr. 1966;9(1):31-36.   Published online January 31, 1966
An autopsy case of a total anomalous pulmonary venous return in an one year and two month old Korean male infant is presented. Five pulmonary veins made a common pulmonary vein and drained into superior vena cava 1.5 cm. above the caval entrance of right atrium. Right atrium was enormously dilated and so was the right ventricle with the wall...
Case Report
Clinical Studies on Congenital Heart Disease (On 135 clinically studied cases)
Chang Yee Hong
Clin Exp Pediatr. 1961;4(2):43-47.   Published online October 31, 1961
During 4 years, from October 1957 to September 1961, 135 cases of congenital heart diseasewere observed, which represents about 1% of the total patients who were seen durng the same period and approximately six times more than the occurence of chronic rheumatic heart disease. Out of the 135 patients, 77 cases(57%) were male and 58 cases(43%) were female. Approxim ately...
Original Article
Studies on Normal Values for Red Blood Cells of Korean Infants and Children.
Chang Yee Hong
Clin Exp Pediatr. 1961;4(2):23-42.   Published online October 31, 1961
Summary 1. This paper presents hematologic data on 1205 samples of blood from normal healthy Korean infants and children ranging in age from birth to 16 years. The number of red blood cells, quantity of hemoglobin, volume of packed cells, the mean corpuscular diameter, and the number of reticulocytes have been determined. The indices of mean corpuscular volume (MCV), mean corpuscular...
Staphyloccal Empyema and Statistical Observation on the Bacterial Resiatance of Staphylococci to the Several Antibiotics.
Chang Yee Hong, Woong Sup Lee, Yoon Bum Kim
Clin Exp Pediatr. 1958;1(3):35-37.   Published online March 31, 1958
1) Out of 6 cases of empyema which were seen in our departmant during the past 6 months, 5 cases were due to coagulase positive staphylococci. 2)The results of the sensitivity tests which were done on the 190 strains of coagulase positive staphylococci which were isolated from various clinical materials from November 1956 to April 1958 are as follow
Abdominal Epilepsy
Chang Yee Hong, Chong En Han
Clin Exp Pediatr. 1958;1(3):57-60.   Published online March 31, 1958
A case of abdominal epilepsy is presented. 1) The pa lent has a positive family history for epilepsy. His one uncle had convulsive seizures during childhood and his three sisters have a history of seizures. 2) The patient had had recurrent convulsions until 6 years of age. 3) Since 7 years of age he had had recurrent paroxysmal abdominal pain which was located mainly...
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